A facile synthesis of 5-substituted 2-furylacetates via 6-hydroxy-3-oxo-4-hexenoates

DOI: 10.1016/0040-4039(95)01612-L

Source and publish data:

Tetrahedron Letters p. 7685 - 7688 (1995)

Update date:2022-08-03

Topics:

Authors:

Kawano, Tomikazu

Ogawa, Toru

Islam, Saiful Md.

Ueda, Ikuo

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0040-4039(95)01612-L

6-Substituted 3-ethoxy-6-hydroxy-2,4-hexadenoates (4) which were prepared by reaction of ethyl (4E)-3-ethoxy-5-formyl-2,4-pentadienoate (3a) with nucleophiles or sodium borohydride reduction of 6-substituted 3-ethoxy-6-oxo-2,4-hexadenoates (3b-e) have been converted in very good yields into 5-substituted 2-furylacetates (5) by treating with 47% HBr in THF.

Full text of DOI:10.1016/0040-4039(95)01612-L

Products guided by the article

Product name:ethyl (2E,4E)-3-ethoxy-6-(4-methoxyphenyl)-6-oxohexa-2,4-dienoate

Cas No:172508-56-4

R&D Labs maybe for 172508-56-4

SHANGHAI RC CHEMICALS CO.,LTD.

website:http://www.rcc.net.cn

Contact:+86-21-50322175

Address:Rm1415 Yinqiao Masion No.58 Jinxin Road Pudong Shanghai China
Phantom-pharma

Contact:

Address:
Shenzhen HwaGen Pharmaceutical Co., Ltd

website:http://www.rafflespt.com

Contact:+86-752-5538396

Address:Guangdong Huizhou China
Huayi Isotopes Co.

Contact:+ 86 512 52491118

Address:1 Fuyu Road, Haiyu TownChangshu, Jiangsu, China
JiangXi Keyuan Biopharma Co., LTD.

Contact:+86-563-6833666

Address:Guangde Fine Chemical Zone, Anhui Province, China

Relevant to this article

Polycarbon ligands: Synthesis and characterization of the phosphinodiynes Ph₂PC≡C-C≡CR (R = Bu^t, Ph, SiMe₃),the μ-η¹,η²_{α, β}-butadiynyl complexes Ru₂(CO)₆-(μ-PPh ₂

Doi:10.1139/v96-262
(1996)
Uranium-sulfilimine chemistry. Hydrolysis of Cp*₂UCl₂ with HNSPh₂·H₂O and the crystal structure of Cp*₂UCl(OH)(HNSPh₂), a metallocene terminal hydroxy complex of tetravalent uranium

Doi:10.1016/j.jorganchem.2004.03.029
(2004)
A highly efficient synthesis of fibrinogen receptor antagonist L-734,217 via a novel chemoselective silyl-mediated conjugate addition of δ-lactams to 4-vinylpyridine

Doi:10.1021/jo951214f
(1996)
Synthesis of 5-methyl-2'-O-deoxycytidine analogs to determine monoclonal antibody specificity in the recognition of the 6-(p-bromobenzoylamino) caproyl radical

Doi:10.1080/07328319708001362
(1997)
A unified strategy for silver-, base-, and oxidant-free direct arylation of C-H bonds

Doi:10.1039/c6gc03438a
(2017)
Polynuclear gold(I) complexes of functionalized thiols and dithiols

Doi:10.1002/cber.19971300515
(1997)

Article Doi