Synthetic studies on condensed-azole derivatives. III. Synthesis and anti- asthmatic activities of C-substituted alkyl side chain derivatives of ω- sulfamoylalkylthioimidazo[1,2-b]pyridazines and related compounds

DOI: 10.1248/cpb.43.1516

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1516 - 1522 (1995)

Update date:2022-08-04

Topics:

Authors:

Kuwahara

Kawano Kawano

Shimazu Shimazu

Yamamoto

Ashida Ashida

Miyake Miyake

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Article abstract of DOI:10.1248/cpb.43.1516

A series of novel alkylthioimidazo[1,2-b]pyridazines was synthesized and evaluated for ability to inhibit platelet activating factor (PAF)-induced bronchoconstriction in guinea pigs. Among them, 3-(imidazo[1,2-h]pyridazin- 6-yl)thio-2,2-dimethylpropanesul

Full text of DOI:10.1248/cpb.43.1516

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