New norepinephrine potentiators: Synthesis and structure-activity relationships of a series of 4-phenyl-1,2,3,4-tetrahydroisoquinolin-4-ols

DOI: 10.1248/cpb.42.67

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 67 - 73 (1994)

Update date:2022-08-04

Topics: Synthesis Structure-activity relationships Norepinephrine Potentiators

Authors:

Kihara Kihara

Kashimoto

Kobayashi

Nagao Nagao

Moritoki

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Article abstract of DOI:10.1248/cpb.42.67

A variety of 1,2,3,4-tetrahydroisoquinolin-4-ols (1-6) were prepared as part of our search for new norepinephrine (NE) potentiators and to clarify the structure-activity relationships. These compounds and some previously prepared compounds were compared w

Full text of DOI:10.1248/cpb.42.67

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