Welcome to LookChem.com Sign In|Join Free

Article Doi

Dispiroketals in Synthesis (Part 19): Dispiroketals as Enantioselective and Regioselective Protective Agents for Symmetric Cyclic and Acyclic Polyols.

DOI: 10.1016/0957-4166(95)00318-J

Source and publish data:

Tetrahedron Asymmetry p. 2403 - 2440 (1995)

Update date:2022-08-05

Topics:

Authors:

Downham, RobertDownham, Robert

Edwards, Paul J.Edwards, Paul J.

Entwistle, David A.Entwistle, David A.

Hughes, Andrew B.Hughes, Andrew B.

Kim, Kun SooKim, Kun Soo

Ley, Steven V.Ley, Steven V.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0957-4166(95)00318-J

The enantioselective preparation of both enantiomers of a C2-symmetric diphenyl-bidihydropyran 3 and 4 is described.The application of enantiopure bi-dihydropyrans 1-4 towards the simultaneous enantioselective differentiation and regioselective protection of a range of cyclic and acyclic symmetrical polyols (23, 37, 43, 45, 54, 61 and 66) is investigated.Several deprotections utilising trifluoroacetic acid (TFA) and a transketalisation with acidic glycerol are presented.

View More

Full text of DOI:10.1016/0957-4166(95)00318-J

Products guided by the article

Product name:(2R,2'R,2''R,3R,4S,6'S,6''S)-1-O,5-O-di-(tert-butyldiphenylsilyl)-3-O,4-O-(6,6'-dimethyl-3,3',4,4',5,5',6,6'-octahydro-2,2'-bi-2H-pyran-2,2'-diyl)-adonitol

Cas No:173397-81-4

173397-81-4

R&D Labs maybe for 173397-81-4

Relevant to this article

Hot Product