Synthesis of highly enantiomerically enriched N-Boc-α-amino ketones from pseudoephedrine N-Boc-α-amino acid amides

DOI: 10.1016/0040-4039(95)02053-5

Source and publish data:

Tetrahedron Letters p. 9429 - 9432 (1995)

Update date:2022-09-26

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Authors:

Myers, Andrew G.

Yoon, Taeyoung

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Article abstract of DOI:10.1016/0040-4039(95)02053-5

N-Boc-α-amino ketones are synthesized efficiently and in high enantiomeric excess by the addition of organolithium and Grignard reagents to pseudoephedrine amides of N-Boc-α-amino acids, themselves available by the alkylation of pseudoephedrine glycinamid

Full text of DOI:10.1016/0040-4039(95)02053-5

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