Enantioselective synthesis of diisopropyl α-, β-, and γ-hydroxyarylalkylphosphonates from ketophosphonates: A study on the effect of the phosphonyl group

Article abstract of DOI:10.1016/0040-4020(95)00855-1

A comparative study of different reduction conditions to an enantioselective synthesis of diisopropyl α-, β- and γ-hydroxyphosphonates 4-6 by 1.3.2-oxazaborolidine catalysis using catecholborane 7 or BH₃·Me₂S 8 is described. The comp