
Journal of the Chemical Society. Perkin transactions I p. 247 - 254 (1996)
Update date:2022-07-30
Topics:
Okawa, Tomohiro
Eguchi, Shoji
Kakehi, Akikazu
The title iminophosphorane 6 has been prepared from methyl 3-aminopyrazine-2-carboxylate 1 by a modified Kirsanov method using a triphenylphosphine-hexachloroethane-triethylamine system. The crystal structure of 6 illustrated an iminophosphorane function (N=P bond). 2,3-Disubstituted pteridin-4(3H)-ones were obtained in a one-pot reaction of 6 with isocyanates, followed by heterocyclization on addition of alcohols or amines.
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