Journal of the Chemical Society. Perkin transactions I p. 157 - 166 (1996)
Update date:2022-09-26
Topics:
Atkinson, Robert S.
Coogan, Michael P.
Cornell, Clive L.
Oxidation of 3-amino-2-trifluoromethylquinazolin-4(3H)-one 6 with lead tetraacetate in dichloromethane gives the title 3-acetoxyamino derivative 7 which is isolable at room temperature and considerably more stable than the corresponding 2-alkyl substituted analogues. Compound 7 aziridinates alkenes in yields which are consistently higher than those from the 2-alkyl substituted analogues. Aziridinations using 3-acetoxyaminoquinazolinones bearing other electron-withdrawing groups on the 2-position of the quinazolinone ring have been examined.
View MoreShanghai Send Pharmaceutical Technology Co., Ltd.
website:http://www.shsendpharma.com
Contact:021-58088081, +8613585868794
Address::Room A601, Building 1,NO. 800 Qingdai Road Pudong District Shanghai,China
Contact:
Address:ROOM 1715, No#345 Jin Xiang Road, Pudong District
BAODING SINO-CHEM INDUSTRY CO.,LTD
Contact:0312-5956088
Address:NO.8 FUXING ROAD,CHINA
Contact:+86-13914766747
Address:Floors 21&22, Jin Cheng Tower, No. 216 Middle Longpan Road, Nanjing
Yicheng Goto Pharmaceuticals Co.,Ltd.
Contact:+86 710 3423122
Address:5th Floor,East Gate of Building #2,Servo-Industrial Park,1st Qilin Road,Xiangyang,Hubei,China
Doi:10.1016/0040-4020(96)00159-7
(1996)Doi:10.1139/v67-385
(1967)Doi:10.1021/ja01520a046
(1959)Doi:10.1248/cpb.44.1647
(1996)Doi:10.1002/chem.201805082
(2019)Doi:10.1134/S1070363220060067
()
