A short asymmetric synthesis of both enantiomers of ramulosin and its analogues

DOI: 10.1055/s-1996-4195

Source and publish data:

Synthesis p. 209 - 214 (1996)

Update date:2022-07-30

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Authors:

Enders, Dieter

Kaiser, Anja

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Article abstract of DOI:10.1055/s-1996-4195

(+)-Ramulosin, a metabolite of Pestalotia ramulosa, and its enantiomer have been synthesized in high enantiomeric purity (ee ≥ 98%) via Michael addition of metalated acetone SAMP-hydrazone (S)-1a to the acetal protected cyclic enoate 2 and subsequent dias

Full text of DOI:10.1055/s-1996-4195

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