Synthesis of a new inhibitor of α-fucosidase

DOI: 10.1016/0960-894X(96)00068-6

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 553 - 558 (1996)

Update date:2022-07-30

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Authors:

Igarashi, Yasuhiro

Ichikawa, Mie

Ichikawa, Yoshitaka

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Article abstract of DOI:10.1016/0960-894X(96)00068-6

A new fucose-type iminosugar in which the nitrogen is placed in the anomeric position was synthesized from D-ribose and was shown to be a potent inhibitor of α-fucosidase (Ki = 8.4 μM).

Full text of DOI:10.1016/0960-894X(96)00068-6

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Product name:5-azido-1-O-benzoyl-5-deoxy-2,3-O-isopropylidene-β-D-ribose

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