The preparation of 2-(2-oxo-2-phenylethyl)benzoic acids from dilithiated ortho-toluic acid

Article abstract of DOI:10.1080/00397919608002615

Ortho-Toluic acid was dimetalated with excess lithium diisopropylamide, and the resulting intermediate was condensed with a variety of aromatic esters to afford new substituted 2-(2-oxo-2-phenylethyl)benzoic acids (ortho-phenacylbenzoic acids).

Full text of DOI:10.1080/00397919608002615

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Synthetic Communications: An
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The Preparation of 2-(2-Oxo-2-
Phenylethyl) Benzoic Acids
from Dilithiated Ortho-Toluic
Acid.
Tina S. Guion a , Madlene U. Koller a , Rene J.
Lachicotte a , Robin N. Rutledge a , Karen C.
Hildebran a , Phuong H. Le a & Charles F. Beam a
a Department of Chemistry and Biochemistry ,
College of Charleston Charleston , South Carolina ,
29424
Published online: 21 Aug 2006.
To cite this article: Tina S. Guion , Madlene U. Koller , Rene J. Lachicotte , Robin
N. Rutledge , Karen C. Hildebran , Phuong H. Le & Charles F. Beam (1996) The
Preparation of 2-(2-Oxo-2-Phenylethyl) Benzoic Acids from Dilithiated Ortho-Toluic
Acid., Synthetic Communications: An International Journal for Rapid Communication
of Synthetic Organic Chemistry, 26:9, 1753-1762, DOI: 10.1080/00397919608002615
To link to this article: http://dx.doi.org/10.1080/00397919608002615
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