Synthesis and resolution of 2-(cyclohexyl-4-(2-quinolylmethoxy)phenyl)methoxyiminopropionic acid, leukotriene biosynthesis inhibitors

DOI: 10.1016/0957-4166(96)00340-0

Source and publish data:

Tetrahedron Asymmetry p. 2645 - 2654 (1996)

Update date:2022-08-04

Topics:

Authors:

Kolasa, Teodozyj

Gunn, David E.

Stewart, Andrew O.

Brooks, Clint D.W.

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Article abstract of DOI:10.1016/0957-4166(96)00340-0

The synthesis and resolution of 2-(E)-(cyclohexyl-4-(2-quinolylmethoxy)-phenyl)methoxyiminopropionic acid 1, a potent leukotriene biosynthesis inhibitor is described. Dibenzoyltartaric acid was used as the chiral auxiliary for the resolution of the hydrox

Full text of DOI:10.1016/0957-4166(96)00340-0

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