Synthesis of a potent inhibitor of β-glucuronidase

DOI: 10.1016/0040-4039(96)00422-4

Source and publish data:

Tetrahedron Letters p. 2707 - 2708 (1996)

Update date:2022-08-04

Topics:

Authors:

Igarashi, Yasuhiro

Ichikawa, Mie

Ichikawa, Yoshitaka

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Article abstract of DOI:10.1016/0040-4039(96)00422-4

A new glucuronic acid-type iminosugar in which a nitrogen atom is placed in the anomeric positon was synthesized and was proven to potently inhibit β-glucuronidase, with Ki = 79 nM.

Full text of DOI:10.1016/0040-4039(96)00422-4

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