Synthesis of 3-(alkylthio and phenylthio)-1,1,1-trifluoroalkan-2-ones via ring opening of epoxy ethers

Article abstract of DOI:10.1055/s-1996-4235

Regioselective ring opening of 1-trifluoromethyl epoxy ethers 2 was achieved with alkyl and phenyl sodium thiolates to afford new 3-(alkylthio and phenylthio)-1,1,1-trifluoroalkan-2-ones 3-5 in good yields.