Chemoenzymatic synthesis of (+)-(4E,15E)-docosa-4,15-dien-1-yn-3-ol, a component of the marine sponge Cribrochalina vasculum

DOI: 10.1039/p19960000961

Source and publish data:

Journal of the Chemical Society. Perkin transactions I p. 961 - 962 (1996)

Update date:2022-09-26

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Authors:

Ohtani, Takehiko

Kikuchi, Keiichi

Kamezawa, Makoto

Hamatani, Hideaki

Tachibana, Hojun

Totani, Tetsuzo

Naoshima, Yoshinobu

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Article abstract of DOI:10.1039/p19960000961

An acetylenic alcohol, (+)-(4E, 15E)-docosa-4,15-dien-1-yn-3-ol 1, isolated from the marine sponge Cribrochalina vasculum, was synthesized in highly enantiomerically pure form by lipase-catalysed transesterification with Novozym 435 (Candida antarctica).

Full text of DOI:10.1039/p19960000961

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