Bioorganic and Medicinal Chemistry Letters p. 1093 - 1098 (1996)
Update date:2022-08-03
Topics:
Dai, Wei-Min
Fong, Kin Chiu
Danjo, Hiroshi
Nishimoto, Sei-Ichi
Solow, Michael
Mak, Wing Leung
Yeung, Mau Lam
A number of novel hydroxy propargylic sulfones 7-15 were synthesized as DNA cleaving agents. Enhancement of DNA cleavage potency was observed with those compounds which could interact with DNA through intercalation of the extended aromatic rings.
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Doi:10.1246/bcsj.69.2123
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(1996)
