Synergistic inhibition of human α-1,3-fucosyltransferase V

DOI: 10.1021/ja960274f

Source and publish data:

Journal of the American Chemical Society p. 7653 - 7662 (1996)

Update date:2022-08-05

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Authors:

Qiao, Lei

Murray, Brion W.

Shimazaki, Makoto

Schultz, Jody

Wong, Chi-Huey

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Article abstract of DOI:10.1021/ja960274f

Human α-1,3-fucosyltransferase V (FucT V), which catalyzes the transfer of L-fucose moiety from guanosine diphosphate β-L-fucose (GDP-Fuc) to an acceptor sugar to form sialyl Lewis x (sLe(x)), was shown to proceed through an ordered, sequential mechanism

Full text of DOI:10.1021/ja960274f

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