Asymmetrie synthesis of (+)-hinokinin, (+)-dihydrocubebin and cubebin dimethyl ether, a new lignan from Phyllanthus niruri

Article abstract of DOI:10.1515/znb-2007-0117

The asymmetric synthesis of the new lignan cubebin dimethyl ether was accomplished in eight steps with an overall yield of 40%. In addition, the known lignans (+)-hinokinin and (+)-dihydrocubebin were synthesized by this route. Our approach involves the h