Tetrahedron Letters p. 4271 - 4274 (1996)
Update date:2022-07-29
Topics:
O'Brien, Peter
Warren, Stuart
Reaction between a phenylalanine-derived aldehyde and a lithiated phosphine oxide (the Hoffmann test) has been used to demonstrate that lithiated phosphine oxides are not configurationally stable in THF at -78°C on the timescale of thier reaction with the aldehyde. Additionally, these reactions generate synthetically useful products. Copyright
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