Synthesis of phenylalanine-derived β-hydroxy and β-keto phosphine oxides -investigation of the configurational stability of lithiated phosphine oxides using the Hoffmann test

DOI: 10.1016/0040-4039(96)00814-3

Source and publish data:

Tetrahedron Letters p. 4271 - 4274 (1996)

Update date:2022-07-29

Topics:

Authors:

O'Brien, Peter

Warren, Stuart

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0040-4039(96)00814-3

Reaction between a phenylalanine-derived aldehyde and a lithiated phosphine oxide (the Hoffmann test) has been used to demonstrate that lithiated phosphine oxides are not configurationally stable in THF at -78°C on the timescale of thier reaction with the aldehyde. Additionally, these reactions generate synthetically useful products. Copyright

Full text of DOI:10.1016/0040-4039(96)00814-3

Products guided by the article

Product name:2-Butanone, 3-[bis(phenylmethyl)amino]-1-(diphenylphosphinyl)-4-phenyl-

Cas No:180585-39-1

R&D Labs maybe for 180585-39-1

Nowa pharmaceuticals Co., LTD

Contact:86-512-69362780,69362785

Address:No.69 Weixin Road,Weiting Town,Suzhou Industrial Park
Shandong Zhongcheng Barium Salt Co., Ltd

Contact:+86-15725732638

Address:No.29 baoxi road, hi-tech zone, zibo, shandong
Shanghai Profirst Co., Ltd.

Contact:+86-21-38122007

Address:2, Lane 1123, Kangqiao Road, Pudong New Area, Shanghai
Chengda Pharmaceuticals Co., Ltd.

Contact:+86-573-84601188

Address:hengshan Road 5# in Jiashan, zhejiang
shijiazhuang baisheng chem co.; ltd

Contact:86-0311-80790826

Address:shijiazhuang hebei

Relevant to this article

A new method to modify the C-4 position of 10-deacetylbaccatin III

Doi:10.1248/cpb.45.2093
(1997)
Copper-Catalyzed Double C-N Bond Formation for the Synthesis of Diverse Benzimidazoles from N -Alkyl-2-iodoaniline and Sodium Azide

Doi:10.1055/s-0036-1588086
(2017)
1-substitution in 2-methyl-4(5)-nitroimidazole. I. Synthesis of compounds with potential antitrichomonal activity.

Doi:10.1021/jm00307a044
(1968)
The preparation of 1H-pyrazole-1-carboxylic acid, 1,1-dimethylethyl esters from dilithiated C(α),N-hydrazones of hydrazinecarboxylic acid, 1,1-dimethylethyl ester

Doi:10.1080/00397919608003780
(1996)
Synthesis of C-oxetanosyl-thiazole and its carbocyclic analog nucleosides as potential chemotherapeutic agents

Doi:10.1016/0960-894X(96)00340-X
(1996)
Lactols in hydrolysates of DNA treated with α-acetoxy-n- nitrosopyrrolidine or crotonaldehyde

Doi:10.1021/tx980165+
(1998)

Article Doi