Bioorganic and Medicinal Chemistry Letters p. 1897 - 1900 (1996)
Update date:2022-07-29
Topics:
Kikuchi, Yoshiko
Nishiyama, Shigeru
Yamamura, Shosuke
Kato, Kuniki
Fujiwara, Sari
Umezawa, Kazuo
Terada, Yukimasa
Novel C-nucleosides (2'S, 3'S)-2-[2',3'-(bishydroxymethyl)-oxetan-1'-yl]-1,3-thiazole-4-carboxam ide 3 and its carbocyclic analog 4 have been synthesized. Compound 4 enhanced NGF-induced differentiation on PC12 cells at 100 μg/ml, and moreover, 4 alone also induced morphological differentiation significantly at 10 and 100 μg/ml.
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Doi:10.1007/BF00807031
(1996)Doi:10.1021/jm960507d
(1996)Doi:10.1021/jo961033t
(1996)Doi:10.1021/jm950896w
(1997)Doi:10.1021/jo961037y
(1996)Doi:10.1007/BF00844218
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