A highly efficient asymmetric synthesis of β-aminophosphonic acids via addition of α-phosphonate carbanions to chiral, enantiopure sulfinimines

DOI: 10.1039/CC9960001503

Source and publish data:

Chemical Communications p. 1503 - 1504 (1996)

Update date:2022-08-03

Topics:

Authors:

Mikolajczyk, Marian

Lyzwa, Piotr

Drabowicz, Jozef

Wieczorek, Michal W.

Blaszczyk, Jaroslaw

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1039/CC9960001503

Addition of α-phosphonate carbanions to (S)-sulfinimines 1 affords N-sulfinyl β-aminophosphonates 2 in a diastereoisomeric ratio from 5:1 to 10:1; the major diastereoisomers of 2, after separation, are converted to the corresponding β-aminophosphonates 3

Full text of DOI:10.1039/CC9960001503

View Online / Journal Homepage / Table of Contents for this issue

View Online

Products guided by the article

Product name:[(R)-2-Phenyl-2-((S)-toluene-4-sulfinylamino)-ethyl]-phosphonic acid dimethyl ester

Cas No:180906-52-9

R&D Labs maybe for 180906-52-9

Henan Techway Chemical Co.,Ltd.

website:http://www.techwaychem.com

Contact:+86-371-66380080

Address:No.27 Shunhe Road,
Shanghai Xinda Pharmaceuticals Co., Ltd.

Contact:86-21-33692333-8008

Address:999 Linxian Road, Jinshan Industrial Park, Shanghai, China
Puyang Willing Chemicals Co.,Ltd.

Contact:86-393-4840366

Address:Puyang Henan China
Shanghai chemrole co.,ltd

Contact:021-50278900

Address:No.6,Room 201 ,Lane 299,bisheng road ,shanghai ,china
SHANDONG ZHANHUA YONGHAO PHARMACEUTICAL TECH.CO.,LTD

Contact:+86-576-88685096

Address:GENGJU VILLAGE NORTH ONE KILOMETER,ZHANHUA DISTRICT,BINZHOU CITY,SHANDONG PROVINCE,CHINA.

Relevant to this article

Doi:10.1016/S0022-328X(00)80305-8
(1975)
A general route to 5-substituted-2-furylacetic acids: a brief synthesis of plakorsin B

Doi:10.1016/j.tetlet.2009.11.120
(2010)
Kinetics of Gas-Phase Addition Reactions of Trichlorosilyl Radicals. 5. Cis-Trans Isomerization of 2-Butene Induced by .SiCl3 Radicals

Doi:10.1021/j100220a014
(1982)
Synthesis and evaluation of coumarin α-methylene-γ-butyrolactones: A new class of platelet aggregation inhibitors

Doi:10.1248/cpb.44.1591
(1996)
A novel fragmentation-cyclization reaction of steroidal α-hydroxy oximes

Doi:10.1016/S0040-4039(98)02166-2
(1998)
2-[(4-Phenylpiperazin-1-yl)methyl]imidazo(di)azines as selective D ₄-ligands. Induction of penile erection by 2-[4-(2-methoxyphenyl) piperazin-1-ylmethyl]imidazo[1,2-a]pyridine (PIP3EA), a potent and selective D₄ partial agonist

Doi:10.1021/jm060166w
(2006)

Article Doi