
Tetrahedron Letters p. 5309 - 5312 (1996)
Update date:2022-08-03
Topics:
Kim, Jong-Man
Wilson, Troy E.
Norman, Thea C.
Schultz, Peter G.
A cyclic urea trimer was synthesized from readily available amino acid derivatives using a simple, iterative approach. A selective amide reduction using borane (BH3-THF) and a triphosgene-mediated cyclization are the key features in a synthesis of the cyclic urea trimer 2.
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