Total synthesis of (-)-cordiaquinone B

Article abstract of DOI:10.1016/0040-4039(96)01556-0

Enantioselective synthesis of the unnatural antipode of cordiaquinone B possessing a 3-substituted 2,3,4-trimethylcyclohexanone framework was accomplished starting with (4S, 5S)-4-methyl-5-trimethylsilyl-2-cyclohexen-1-one. By this synthesis, the absolute structure of (+)-cordiaquinone B has been established.