On the binding site of quinolone antibacterials. An attempt to probe the Shen model

DOI: 10.1016/0960-894X(96)00430-1

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 2333 - 2338 (1996)

Update date:2022-08-03

Topics: Experimental terms Binding site Probing

Authors:

Hanessian, Stephen

Saladino, Raffaele

Nunez, Jose Cid

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Article abstract of DOI:10.1016/0960-894X(96)00430-1

Quinolone-nuclei acid base hybrids were synthesized in an effort to probe a mechanistic model and a proposed mode of antibacterial action where stacked pairs of quinolones interact with DNA through H-bonding.

Full text of DOI:10.1016/0960-894X(96)00430-1

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