On the binding site of quinolone antibacterials. An attempt to probe the Shen model

DOI: 10.1016/0960-894X(96)00430-1

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 2333 - 2338 (1996)

Update date:2022-08-03

Topics: Experimental terms Binding site Probing

Authors:

Hanessian, Stephen

Saladino, Raffaele

Nunez, Jose Cid

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0960-894X(96)00430-1

Quinolone-nuclei acid base hybrids were synthesized in an effort to probe a mechanistic model and a proposed mode of antibacterial action where stacked pairs of quinolones interact with DNA through H-bonding.

Full text of DOI:10.1016/0960-894X(96)00430-1

Products guided by the article

Product name:(Z)-3-[4-(4-Amino-2-oxo-2H-pyrimidin-1-yl)-butylamino]-2-(2,4-dichloro-5-fluoro-benzoyl)-acrylic acid ethyl ester

Cas No:182627-54-9

R&D Labs maybe for 182627-54-9

Zibo Ocean International Trade Co.,Ltd(expird)

Contact:+86 533 5160706

Address:1117, Hongtai Bld., Songling rd, Zichuan,Zibo,Shandong,China
Shanghai Bosman Industrial Co., Ltd

Contact:86-21-63065878-8006

Address:Rm907, No.1611, North Sichuan Road, Hongkou District, Shanghai, 200080 China
Goldwills Pharmaceuticals Co., Ltd.

Contact:0916-2237889 13991621155

Address:North Suburb of Hanzhong city, Shaanxi Province
N&R INDUSTRIES,INC

Contact:Tel:+86-29-88764861 Fax:+86-29-88764861

Address:Rm#2107, Block A, Epin Meidao Building, Gaoxin Rd, Hi-Tech Zone, Xi’an, China
sichuan tiancai fine co LTD.

website:http://www.tcfinechem.com/

Contact:18681346930

Address:baifu town,whou district

Relevant to this article

2,3-DICARBOMETHOXY-1,3-BUTADIENE AND ITS REACTIONS

Doi:10.1016/S0040-4039(00)96942-9
(1987)
Synthesis of vinylallenes by conjugate 1,6-, 1,8-, 1,10- and 1,12-addition reactions of organocuprates with acetylenic Michael acceptors and their use as dienes in intermolecular Diels-Alder reactions

Doi:10.1002/jlac.199619961002
(1996)
Asymmetric epoxidation of chiral allylic alcohols

Doi:10.1016/0957-4166(96)00327-8
(1996)
Synthesis of certain derivatives of 3-phenyl-5-methyl-4-isoxazolearboxylic acid

Doi:10.1007/BF00760824
(1968)
Laboratory evolution of robust and enantioselective Baeyer-Villiger monooxygenases for asymmetric catalysis

Doi:10.1021/ja906212k
(2009)
Prostaglandin E₂-bisphosphonate conjugates: Potential agents for treatment of osteoporosis

Doi:10.1016/S0968-0896(99)00045-0
(1999)

Article Doi