Tetrahedron Letters p. 6457 - 6460 (1996)
Update date:2022-08-05
Topics:
Kofoed, Thomas
Caruthers, Marvin H.
5'-Deoxy-5'-phosphonothymidine was synthesized and coupled with 3'-deoxy-3'-hydroxy-methylthymidine to yield a 3'-C-O-P-5' linked thymidine dinucleotide. This dimer as its 3'-phosphoramidite was used to synthesize deoxyoligonucleotides.
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