A General Route for the Synthesis of Pyrimidothienopyridazine Derivatives

DOI: 10.1007/BF00817265

Source and publish data:

Monatshefte fur Chemie p. 739 - 746 (1996)

Update date:2022-08-05

Topics:

Authors:

Quintela, J. M.

Veiga, M. C.

Conde, S.

Peinador, C.

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Article abstract of DOI:10.1007/BF00817265

A facile synthesis of 8-substituted pyrimido<4',5':4,5>thieno<2,3-c>pyridazines (6a-i) has been accomplished.The sequence involves the ring closure of a heterocyclic aminonitrile precursor (3) after reaction with (dichlomethylene)-dimethylammonium chloride. - Keywords: Pyrimido<4',5':4,5>thieno<2,3-c>pyridazine derivatives; Thieno<2,3-c>pyridazine-6-carbonitrile; N,N-Dimethyldichloromethyleniminium chloride; Enaminonitrile

Full text of DOI:10.1007/BF00817265

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