A convergent enantioselective synthesis of the tetrahydroisoquinoline unit in the spiro ring of ecteinascidin 743

DOI: 10.1016/0040-4039(96)01622-X

Source and publish data:

Tetrahedron Letters p. 7163 - 7166 (1996)

Update date:2022-08-02

Topics:

Authors:

Corey Corey

Gin, David Y.

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Article abstract of DOI:10.1016/0040-4039(96)01622-X

An efficient enantioselective synthesis of the spiro tetrahydroisoquinoline unit in ecteinascidin 743 is described, employing (+)-tetrahydrocarvone as a readily available and recoverable chiral auxiliary. The synthetic sequence involves a triply-convergen

Full text of DOI:10.1016/0040-4039(96)01622-X

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