Directing Effects in Homogeneous Hydrogenation with PF6

DOI: 10.1021/jo00364a007

Source and publish data:

Journal of Organic Chemistry p. 2655 - 2661 (1986)

Update date:2022-08-02

Topics:

Authors:

Crabtree, Robert H.

Davis, Mark W.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00364a007

The presence of a ligating group, e.g., OH, CO2Me, C=O, or OMe, on an olefinic substrate is shown to direct the attack of the hydrogenation catalyst PF6/H2/CH2Cl2 from the face of the molecule containing the directing group.Isomerization is a minor side reaction in the cases studied.The origin of this effect is discussed and a model intermediate isolated.

Full text of DOI:10.1021/jo00364a007

Products guided by the article

Product name:1-acetyl-4-methylcyclohexane

Cas No:18446-88-3

R&D Labs maybe for 18446-88-3

Allicon Pharmaceuticals,Inc.

Contact:+86-519-86339586，13584329896

Address:Changzhou Scientific and Education Park
Hangzhou Neway Chemicals Co., Ltd.

Contact:+86-571-85095566

Address:Room 803, Qinglian Bldg, No 139 Qingchun Road, Hangzhou, Zhejiang China
Sichuan JieYao Co., Ltd.

Contact:+86-838-5655598

Address:Guanghan Nanfeng Industrial Zone
Triumph International Development Limilted

website:http://www.jiashengchem.cn/

Contact:+86-536-7971999

Address:Yinhai Road,Shouguang
shanghai meicheng chemical co .,ltd(expird)

Contact:+86-21-50677091

Address:Room 302, Building 7, No.1000, Jinhai Road

Relevant to this article

Radical substitution in the nickeladithiolene ring in bis(1-phenyl-1,2-ethenedithiolato)nickel(0)

Doi:10.1021/om960698i
(1996)
Two approaches to the enantioselective synthesis of (4R)-(-)-4-hydroxymethyl-4-thiobutyro-1,4-lactone

Doi:10.1016/S0957-4166(99)00568-6
(2000)
Optical resolution by preferential crystallization of (RS)-2-benzoylamino-2-benzyl-3-hydroxypropanoic acid and its use in synthesizing optically active 2-amino-2-methyl-3-phenylpropanoic acid.

Doi:10.1248/cpb.50.1362
(2002)
Design, synthesis, and evaluation of a depsipeptide mimic of tendamistat

Doi:10.1021/jo9616062
(1997)
Electrophilic methylplatinum complexes: First structure of a hydroxytris(pentafluorophenyl)borate complex

Doi:10.1021/om960834j
(1997)
A novel route to pentacoordinated organylsilanes and -germanes

Doi:10.1016/S0022-328X(97)00454-3
(1997)

Article Doi