Directing Effects in Homogeneous Hydrogenation with PF6

DOI: 10.1021/jo00364a007

Source and publish data:

Journal of Organic Chemistry p. 2655 - 2661 (1986)

Update date:2022-08-02

Topics:

Authors:

Crabtree, Robert H.

Davis, Mark W.

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Article abstract of DOI:10.1021/jo00364a007

The presence of a ligating group, e.g., OH, CO2Me, C=O, or OMe, on an olefinic substrate is shown to direct the attack of the hydrogenation catalyst PF6/H2/CH2Cl2 from the face of the molecule containing the directing group.Isomerization is a minor side reaction in the cases studied.The origin of this effect is discussed and a model intermediate isolated.

Full text of DOI:10.1021/jo00364a007

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