Monatshefte fur Chemie p. 31 - 43 (1990)
Update date:2022-08-02
Topics:
Doyle, Thomas R.
Vogl, Otto
Fluorochlorobromoacetic acid was synthesized in the sequence of four steps from 1,1,2-trifluoro-2-chloroethylene in an overall yield of approximately 25percent. 1,1,2-Trifluoro-2-chloroethylene was first allowed to react with sodium methoxide to form 1,2-difluoro-1-chloro-2-methoxyethylene, which was then brominated with elemental bromine and the reaction product treated with concentrated sulfuric acid to give methyl fluorochlorobromoacetate.This compound was hydrolized with a diluted sodium hydroxide solution to fluorochlorobromoacetic acid.
View MoreJinan Kaypharm Chemical Co.,Ltd
Contact:86-0531-86986780
Address:Room101,No189-2,Huayuan Road,Jinan City,Shandong Province
shijiazhuang shuanglian chemical industry co.,ltd
Contact:0311-82190302
Address:Luquan Intersection , Shijiazhuang--Taiyuan Expressway，Shijiazhuang City
Zhejiang Chemline International Co., Ltd.
Contact:+86-571-88062298
Address:Hengdian Industry Area, Dongyang, Zhejiang, China
Ningbo Tide Imp. & Exp. Co., Ltd.
Contact:+86-571-8993 7933; +86-571-8993 6453
Address:7/F Anno Domini Building, Tower South, 8 Qiu Shi Road,Hangzhou,China.
MedicalChem(Yancheng)Manuf.Co.,Ltd.
Contact:+86-515-84383366
Address:Touzeng BinHai, YanCheng City, JiangSu Province, China
Doi:10.1016/S0040-4039(01)98921-X
(1968)Doi:10.1021/ja963008a
(1997)Doi:10.1139/V08-133
(2009)Doi:10.1021/ol201378w
(2011)Doi:10.1055/s-1991-26388
(1991)Doi:10.1021/ol016285h
(2001)
