Bioorganic and Medicinal Chemistry Letters p. 1863 - 1868 (1999)
Update date:2022-07-30
Topics:
Rodriguez, Michael J.
Vasudevan, Vasu
Jamison, James A.
Borromeo, Peter S.
Turner, William W.
A facile synthesis of phosphonate and phosphate ester prodrugs on the phenolic hydroxy of two echinocandin semisynthetic derivatives is reported. The water solubility and stability profiles of the ECB compounds varied with the choice of alkyl group used.
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