The first enantioselective synthesis of optically pure (R)- and (S)- 5,5''-dihydroxy-4',4''',7,7''-tetramethoxy-8,8''- biflavone and the reconfirmation of their absolute configuration

DOI: 10.1016/S0040-4039(96)02475-6

Source and publish data:

Tetrahedron Letters p. 1087 - 1090 (1997)

Update date:2022-08-03

Topics:

Authors:

Lin, Guo-Qiang

Zhong, Min

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(96)02475-6

The first enantioselective synthesis of the optically pure (R)- and (S)-5,5''-dihydroxy-4',4''',7,7''-tetramethoxy-8,8''- biflavone is described. The key steps involve the intramolecular oxidative coupling of the cyanocuprate intermediate and Friedel-Crafts rearrangement. Their absolute configuration was reconfirmed by CD spectra.

Full text of DOI:10.1016/S0040-4039(96)02475-6

Products guided by the article

Product name:(2R,3R)-1,4-Bis-benzyloxy-3-(tert-butyl-dimethyl-silanyloxy)-butan-2-ol

Cas No:187404-33-7

R&D Labs maybe for 187404-33-7

suzhou chukai pharmateach co,.ltd

Contact:86-512-88812511

Address:Building 3, Wujiang Scientific Innovation Park, 2358 Changan Rd, Wujiang 215200, Jiangsu Province, P. R. China
HEBEI BRANT PHARMACEUTICAL

Contact:+86-0311-84455288-844

Address:Mayu Industrial Park, Jinzhou, Hebei, China.
TAIZHOU XINGCHENG CHEMPHARM CO.,LTD.

Contact:0086-0576-88551200,88886292 ,88880039

Address:B Area. 10 Floor.Yaodadasha. 289#.Shifu Road.Taizhou.Zhejiang.China
Xiamen XM-Innovation Chemical Co., Ltd

Contact:+86-592-3216205

Address:Unit Q, 11/F, No.1 Office Building, Wuyuan Bay Business Center, Huli District, Xiamen City, Fujian Province, P.R.C
Dalian Join King Biochemical Tech. Co., Ltd.

Contact:0411 39216206

Address:814 First State Blvd

Relevant to this article

Acceleration of hydrolytic DNA cleavage by dicopper(II) complexes with p-cresol-derived dinucleating ligands at slightly acidic pH and mechanistic insights

Doi:10.1246/bcsj.20180353
(2019)
A nonpeptidic agonist ligand of the human C5a receptor: Synthesis, binding affinity optimization and functional characterization

Doi:10.1016/S0960-894X(96)00606-3
(1997)
Doi:10.1021/ja01493a051
(1960)
Discovery of novel quinoline sulphonamide derivatives as potent, selective and orally active RORγ inverse agonists

Doi:10.1016/j.bmcl.2019.05.015
(2019)
Intramolecular benzoate exchange in benzoato meso-tetra (4-methoxyphenylporphyrinato) thallium(III), Tl(tmpp)(C₆H₅CO₂)

Doi:10.1016/S0277-5387(96)00479-2
(1997)
Tandem reduction-olefination of triethyl 2-acyl-2-fluoro-2-phosphonoacetates and a synthetic approach to Cbz-Gly-Ψ[(Z)-CF{double bond, long}C]-Gly dipeptide isostere

Doi:10.1016/j.tet.2006.09.096
(2006)

Article Doi