Heterocyclic analogues of quinone methide: Preparation and cytotoxicity of 3-oxo-3H-pyrazolo[1,5-a]indole derivatives

DOI: 10.1248/cpb.45.143

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 143 - 147 (1997)

Update date:2022-08-04

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Authors:

Katayama, Hajime

Tagawa, Naoyuki

Kawada, Yusuke

Shiobara, Keiichi

Kaneko, Kimiyoshi

Honda, Yurie

Kondo, Noriko

Ikeda, Yoshiaki

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Article abstract of DOI:10.1248/cpb.45.143

A series of 3-oxo-3H-pyrazolo[1,5-a]indole derivatives was prepared and characterized as heterocyclic analogues of quinone methide. These compounds showed some cytotoxicity to cancer cells, but were ineffective in an in vivo test against murine leukemia L

Full text of DOI:10.1248/cpb.45.143

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