
Tetrahedron p. 3045 - 3056 (1997)
Update date:2022-08-02
Topics:
Lee, Yong Sup
Kang, Soo Sung
Choi, Jung Hoon
Park, Hokoon
A chiral synthesis of functionalized benzo[a]quinolizine derivative (5) has been accomplished starting from a chiral lactone 7. The key feature is the efficient control of the stereochemistry of ring juncture of the functionalized benzo[a]quinolizine derivative 5 by the N-acyliminium ion cyclization of chiral lactam 11b.
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Doi:10.1016/0960-894X(96)00484-2
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