An efficient synthesis of a Galβ1-3GalNAc-serine derivative using β-galactosidase

DOI: 10.1016/S0040-4039(97)00019-1

Source and publish data:

Tetrahedron Letters p. 1211 - 1214 (1997)

Update date:2022-08-05

Topics:

Authors:

Suzuki, Katsuhiko

Fujimoto, Hiroshi

Ito, Yoshiyuki

Sasaki, Takashi

Ajisaka, Katsumi

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(97)00019-1

An efficient route for the synthesis of Galβ1-3GalNAcα1-O-serine derivative was developed using a novel β1-3 galactosidase obtained from Bacillus circulans. By a transglycosylation reaction with pNP-β-Gal 2 as a donor and GalNAcα1-O-Z-Ser-OAll 4 as an acceptor, Galβ1-3GalNAcα-1-O-Z-Ser-OAll 5 was synthesized in 68% yield.

Full text of DOI:10.1016/S0040-4039(97)00019-1

Products guided by the article

Product name:N-(benzyloxycarbonyl)-O-(β-D-galactopyranosyl)-(1->3)-O-(2-acetamido-2-deoxy-α-D-galactopyranosyl)-(1->3)-L-serine allyl ester

Cas No:188641-26-1

R&D Labs maybe for 188641-26-1

Shanghai Yudiao Chemistry Technology Co.,Ltd

Contact:0086-18964703211

Address:Building NO.5, NO.218,Rongtian Road,ganxiang town,Jinshan District,shanghai,201518,china
Geen Chemical Technology Co., Ltd

Contact:86-769-21660847

Address:1408, Yingfeng Commercial Center, Nancheng District
shanghai payne pharm co.,ltd.

Contact:+86-021-58123769

Address:No.780 of Cailun Road,Zhangjiang Hi-tech Park,Pudong,Shanghai
NingBO Hong Xiang Biochem.Co.Ltd

website:http://www.hxbiochem.com

Contact:0574-66003444

Address:Ning Bo Bei Lun
Langchem

Contact:+86+21-58956006 15800617331

Address:402 Room, 150# Cailun Road, Zhangjiang high tech park, Shanghai

Relevant to this article

Synthesis of kojidextrins and their protein conjugates. Incidence of steric mismatch in oligosaccharide synthesis

Doi:10.1021/jo962300y
(1997)
Stereoselective synthesis of [2S,3R]-β-hydroxy ornithine

Doi:10.1080/00397919708006062
(1997)
Diastereoselective addition of organomagnesium and organolithium reagents to chiral trifluoromethyl N-tert-butanesulfinyl hemiaminals

Doi:10.1002/ejoc.201300890
(2013)
Hydrazinium heptafluorouranate(V). Preparation, properties, and thermal decomposition

Doi:10.1021/ic50038a010
(1966)
Electrochemical removal of the picolinoyl group under mild acidic conditions, application to the protection of amines in peptide synthesis

Doi:10.1016/S0040-4039(97)00362-6
(1997)
Macrophomate synthase: Unusual enzyme catalyzing multiple reactions from pyrones to benzoates

Doi:10.1016/S0040-4039(99)01441-0
(1999)

Article Doi