Chemical and Pharmaceutical Bulletin p. 437 - 445 (1997)
Update date:2022-08-04
Topics: Experimental terms Chemical terms
Ogihara, Kazuhito
Yamashiro, Rieko
Higa, Matsutake
Yogi, Seiichi
Various naphthoquinone derivatives were prepared from a natural product, 5-hydroxy-2-methyl-1,4-naphthoquinone (plumbagin); these were mostly substituted at C-3 through carbon-carbon bond formation mediated by a metal- based oxidant such as lead tetraacetate in the presence of various carboxylic acids. The halogenated compounds showed stronger ichthyotoxicity than plumbagin, but other derivatives were less active.
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(1997)Doi:10.1023/A:1025611727728
(2003)Doi:10.1016/0040-4020(96)00296-7
(1996)Doi:10.1016/S0040-4020(97)00162-2
(1997)Doi:10.1080/00397919708006073
(1997)