Synthesis of a pyrimido[4,5-b]azepine analog of 5,10-dideaza-5,6,7,8-tetrahydrofolic acid (DDATHF)

DOI: 10.1016/S0960-894X(97)00041-3

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 453 - 456 (1997)

Update date:2022-08-03

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Authors:

Taylor, Edward C.

Dowling, James E.

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Article abstract of DOI:10.1016/S0960-894X(97)00041-3

The synthesis and biological evaluation of a pyrimido[4,5-b]azepine-based analog of DDATHF, a potential chemotherapeutic agent, are described.

Full text of DOI:10.1016/S0960-894X(97)00041-3

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Product name:Benzoic acid, 4-[2-(hexahydro-7-oxo-1H-azepin-4-yl)ethyl]-, methyl ester

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