Stereoselective synthesis and receptor activity of conformationally defined retinoid X receptor selective ligands

DOI: 10.1016/S0960-894X(99)00048-7

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 589 - 594 (1999)

Update date:2022-08-04

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Authors:

Vuligonda, Vidyasagar

Garst, Michael E.

Chandraratna, Roshantha A.S.

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Article abstract of DOI:10.1016/S0960-894X(99)00048-7

Retinoid X Receptor (RXR) specific ligands are currently being investigated for the treatment of metabolic diseases such as type II diabetes. We report the synthesis of conformationally locked retinoids, which are potent RXR selective ligands, and the att

Full text of DOI:10.1016/S0960-894X(99)00048-7

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