Synthesis and cytotoxic activity of alkylidene- and alkyl-substituted camptothecins

DOI: 10.1016/S0960-894X(97)00105-4

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 847 - 850 (1997)

Update date:2022-08-02

Topics:

Authors:

Candiani, Ilaria

Bedeschi, Angelo

Cabri, Walter

Zarini, Franco

Visentin, Giuseppina

Capolongo, Laura

Geroni, Cristina

Ciomei, Marina

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0960-894X(97)00105-4

A new family of camptothecin derivatives is described. Their synthesis, in vitro cytotoxicity, and topoisomerase I inhibition is reported.

Full text of DOI:10.1016/S0960-894X(97)00105-4

Products guided by the article

Product name:(S)-4-Ethyl-4-hydroxy-10-((E)-styryl)-1,12-dihydro-4H-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione

Cas No:189311-99-7

R&D Labs maybe for 189311-99-7

HEZE KINGVOLT CHEMICAL CO., LTD

Contact:86-573-82118911

Address:Juancheng Industry Park
Xiamen Hisunny Chemical Co.,Ltd

website:http://www.hisunnychem.com

Contact:+86-592-3327115

Address:Unit 603,No.879,Xiahe Road,Meixin Building,Xiamen,China
Jinan Kaypharm Chemical Co.,Ltd

Contact:86-0531-86986780

Address:Room101,No189-2,Huayuan Road,Jinan City,Shandong Province
Zhejiang Kente Chemical Co.,Ltd.

Contact:86-0576-87651912

Address:No.7, Fengxi West Road, Modern Industrial Zone
Shanghai Send Pharmaceutical Technology Co., Ltd.

website:http://www.shsendpharma.com

Contact:021-58088081, +8613585868794

Address::Room A601, Building 1,NO. 800 Qingdai Road Pudong District Shanghai,China

Relevant to this article

Synthesis and biological evaluation of 3-heteroaryloxy-4-phenyl-2(5H)-furanones as selective COX-2 inhibitors

Doi:10.1016/S0960-894X(99)00560-0
(1999)
The first evidence of insertion of isocyanide into a metal-sulfur bond: Catalytic and stoichiometric behavior of isocyanide and thiolate ligands on palladium and platinum

Doi:10.1021/ja970518b
(1997)
Synthesis of several dibasic acid esters of 3-quinuclidinol as potential pharmacological agents.

Doi:10.1002/jps.2600570432
(1968)
New Semiconducting Polymer Based on Benzo[1,2-b:4,5-b′]diselenophene Donor and Diketopyrrolopyrrole/Isoindigo Acceptor Unit: Synthesis, Characterization and Photovoltaics

Doi:10.1002/cjoc.201500270
(2015)
Absolute pK_as of Sulfonamides in Ionic Liquids: Comparisons to Molecular Solvents

Doi:10.1021/acs.joc.6b02182
(2016)
Doi:10.1021/jf60158a021
(1968)

Article Doi