Synthesis and cytotoxic activity of alkylidene- and alkyl-substituted camptothecins

DOI: 10.1016/S0960-894X(97)00105-4

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 847 - 850 (1997)

Update date:2022-08-02

Topics:

Authors:

Candiani, Ilaria

Bedeschi, Angelo

Cabri, Walter

Zarini, Franco

Visentin, Giuseppina

Capolongo, Laura

Geroni, Cristina

Ciomei, Marina

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Article abstract of DOI:10.1016/S0960-894X(97)00105-4

A new family of camptothecin derivatives is described. Their synthesis, in vitro cytotoxicity, and topoisomerase I inhibition is reported.

Full text of DOI:10.1016/S0960-894X(97)00105-4

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