Bioorganic and Medicinal Chemistry Letters p. 3187 - 3192 (1999)
Update date:2022-08-02
Topics:
Lau, Cheuk K.
Brideau, Christine
Chan, Chi Chung
Charleson, Stella
Cromlish, Wanda A.
Ethier, Diane
Yves Gauthier, Jacques
Gordon, Robert
Guay, Jocelyne
Kargman, Stacia
Li, Chun-Sing
Prasit, Petpiboon
Riendeau, Denis
Therien, Michel
Visco, Denise M.
Xu, Lijing
A series of 3-heteroaryloxy-4-phenyl-2-(5H)-furanones were prepared and evaluated for their potency and selectivity as COX-2 inhibitors. This led to the identification of L-778,736 as a potent, orally active and selective inhibitor of the COX-2 enzyme.
View Moresuzhou chukai pharmateach co,.ltd
Contact:86-512-88812511
Address:Building 3, Wujiang Scientific Innovation Park, 2358 Changan Rd, Wujiang 215200, Jiangsu Province, P. R. China
shanghai meicheng chemical co .,ltd(expird)
Contact:+86-21-50677091
Address:Room 302, Building 7, No.1000, Jinhai Road
Hangzhou Neway Chemicals Co., Ltd.
Contact:+86-571-85095566
Address:Room 803, Qinglian Bldg, No 139 Qingchun Road, Hangzhou, Zhejiang China
ZHEJIANG JIANYE CHEMICAL CO.,LTD.
Contact:86-571-64149273,64149234
Address:No. 48, Fuxi Road, Meicheng Town
Hangzhou Hysen Pharma co.,Ltd.
website:http://www.hysenpharma.cn/
Contact:0086-571-88298791
Address:#701,Gudun Road Hangzhou
Doi:10.1021/jf60158a021
(1968)Doi:10.1016/S0040-4039(97)00665-5
(1997)Doi:10.1002/cber.19971300604
(1997)Doi:10.1055/s-1999-3456
(1999)Doi:10.1080/00945719708000216
(1997)Doi:10.1016/S0008-6215(97)00047-5
(1997)
