PPL-catalysed hydrolysis of 3,4-disubstituted β-lactams: Effect of chain length and stereochemistry on the enantioselectivity

DOI: 10.1016/S0040-4020(98)00313-5

Source and publish data:

Tetrahedron p. 6529 - 6538 (1998)

Update date:2022-09-26

Topics:

Authors:

Basak, Amit

Bhattacharya, Gautam

Bdour, Hussam M.M.

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Article abstract of DOI:10.1016/S0040-4020(98)00313-5

3,4-Disubstituted β-lactam acetates 1a-15a have been subjected to PPL- catalysed hydrolysis. The stereochemical course of hydrolysis has been shown to depend upon the C3-C4 relative stereochemistry and the length of the chain bearing acetate functionality.

Full text of DOI:10.1016/S0040-4020(98)00313-5

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