
Tetrahedron Letters p. 2317 - 2320 (1997)
Update date:2022-08-05
Topics:
Nicolas, Ernesto
Pujades, Montse
Bacardit, Jordi
Giralt, Ernest
Albericio, Fernando
The use of N-Fmoc-N-(Hmb)amino acids for the introduction of the Hmb backbone protection into peptides during solid-phase synthesis is described. An efficient two step synthesis of these derivatives is reported and their coupling to the peptide chain is studied.
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(1997)