Synthesis and evaluation of oligodeoxynucleotides containing 3'-C- aminomethyl- and 3'-C-methylthymidine

Article abstract of DOI:10.1080/07328319708001361

3'-C-Aminomethyl- and 3'-C-methylthymidine were synthesized and incorporated into oligodeoxynucleotides. Hybridization and enzyme stability of the modified oligonucleotides containing the 3'-C-branched thymidines are discussed.

Full text of DOI:10.1080/07328319708001361

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Nucleosides and Nucleotides
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Synthesis and Evaluation of
Oligodeoxynucleotides Containing
3′-C-Aminomethyl-and 3′-C-
Amethylthymidine
Guangyi Wang a , Patrick J. Middleton a , Liyan He a , Vesna
Stoisavljevic a & Wiliiied E. Seifert a
a Research Department , ICN Pharmaceuticals, Inc. , 3300
Hyland Avenue, Costa Mesa, CA, 92626, USA
Published online: 21 Aug 2006.
To cite this article: Guangyi Wang , Patrick J. Middleton , Liyan He , Vesna Stoisavljevic &
Wiliiied E. Seifert (1997) Synthesis and Evaluation of Oligodeoxynucleotides Containing 3′-C-
Aminomethyl-and 3′-C-Amethylthymidine, Nucleosides and Nucleotides, 16:4, 445-454, DOI:
10.1080/07328319708001361
To link to this article: http://dx.doi.org/10.1080/07328319708001361
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