Synthesis of Modified Tripeptides and Tetrapeptides as Potential Bisubstrate Inhibitors of the Epidermal Growth Factor Receptor Protein Tyrosine Kinase

DOI: 10.1002/hlca.19970800304

Source and publish data:

Helvetica Chimica Acta p. 653 - 670 (1997)

Update date:2022-08-05

Topics:

Authors:

Mett, Helmut

Furet, Pascal

Traxler, Peter

Fretz, Heinz

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Article abstract of DOI:10.1002/hlca.19970800304

Thesynthesis of a series of bisubstrate inhibitors of the epiermal growth factor receptor protein kinase (EGF-R PTK) consisting of small peptides linked covalently to adenosine via appropriate triphosphate substitutes is described.Boc-Glu(O'Bu)-Tyr-Leu-OB

Full text of DOI:10.1002/hlca.19970800304

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