A concise synthetic entry to substituted 2-Aminothieno[2,3- d]pyrimidines via a Gewald precursor

DOI: 10.1016/S0960-894X(97)00283-7

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 1629 - 1634 (1997)

Update date:2022-08-03

Topics:

Authors:

Zhang, Minsheng

Harper, Richard W.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0960-894X(97)00283-7

A concise synthesis of substituted 2-aminothieno[2,3-d]pyrimidines is described based on pyrimidine annulation of tetrasubstituted thiophene precursors assembled by a Gewald thiophene ring synthesis.

Full text of DOI:10.1016/S0960-894X(97)00283-7

Products guided by the article

Product name:Benzenebutanoic acid, b-oxo-4-(phenylmethoxy)-a-[4-(phenylmethoxy)phenyl]-, methyl ester

Cas No:193697-98-2

R&D Labs maybe for 193697-98-2

Yantai Derun Liquid Crystal Materials Co. Ltd.

website:http://www.ytderun.com

Contact:86-535-6300169

Address:ROOM 90, XIANGFU STREET, FUSHAN NEW-HIGH-TECH IDUSTRY ZONE, YANTAI
Xiamen XM-Innovation Chemical Co., Ltd

Contact:+86-592-3216205

Address:Unit Q, 11/F, No.1 Office Building, Wuyuan Bay Business Center, Huli District, Xiamen City, Fujian Province, P.R.C
Tosta Enterprise Co., Ltd.

Contact:+86-134-5286-9121

Address:Add: Wing Tuck Commercial Centre, 177-183 Wing Lok Street, Hong Kong,
Zhejiang Kaili Industrial Co., Ltd

Contact:+86-571-85241926

Address:lantian business center,No.18 Moganshan Road
Shandong Jusage Technology Co.,Ltd.

Contact:86-13406130167

Address:No.20,North Ride No.9 Road, Guangrao Economic Development Zone, Shandong Province

Relevant to this article

Tyrosine kinase inhibitors. 14. Structure-activity relationships for methyl-amino-substituted derivatives of 4-[3-bromophenyl)amino]-6- (methylamino)-pyrido[3,4-d]pyrimidine (PD 158780), a potent and specific inhibitor of the tyrosine kinase activity of receptors for the EGF family of growth factors

Doi:10.1021/jm970641d
(1998)
Doi:10.1021/ja01310a036
(1935)
A new efficient method for the three-component synthesis of 4(3H)-Quinazolinones

Doi:10.3987/COM-08-11437
(2008)
Doi:10.1002/jps.2600571039
(1968)
Pd-catalyzed carbonylative cycloamidation of ketoimines for the synthesis of pyrido[1,2-a]pyrimidin-4-ones

Doi:10.1039/c5cc02631h
(2015)
Palladium-Catalyzed Additions of Alkenyl Epoxides to Pronucleophiles: A Synthesis of the Macrolactam Aglycone of Fluviricin B1

Doi:10.1002/anie.199714861
(1997)

Article Doi