A concise synthetic entry to substituted 2-Aminothieno[2,3- d]pyrimidines via a Gewald precursor

DOI: 10.1016/S0960-894X(97)00283-7

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 1629 - 1634 (1997)

Update date:2022-08-03

Topics:

Authors:

Zhang, Minsheng

Harper, Richard W.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0960-894X(97)00283-7

A concise synthesis of substituted 2-aminothieno[2,3-d]pyrimidines is described based on pyrimidine annulation of tetrasubstituted thiophene precursors assembled by a Gewald thiophene ring synthesis.

Full text of DOI:10.1016/S0960-894X(97)00283-7

Products guided by the article

Product name:Benzenebutanoic acid, b-oxo-4-(phenylmethoxy)-a-[4-(phenylmethoxy)phenyl]-, methyl ester

Cas No:193697-98-2

R&D Labs maybe for 193697-98-2

HEZE KINGVOLT CHEMICAL CO., LTD

Contact:86-573-82118911

Address:Juancheng Industry Park
Jiangxi Global Natural Spice Co., Ltd.

Contact:+86-796-8106598

Address:No.89, Wenshan Road,South Industrial Park, Jishui County,Jiangxi Province
Antimex Chemical Limied

website:http://www.antimex.com

Contact:0086-21-50563169

Address:Room1027,No.Jinyu Road,Pudong
ZHIJIANG ZENVA SINO COMMERCE AND TRADE CO., LTD.

website:http://www.zenvasino.com

Contact:+86-138-72658998

Address:Shibeishan Road,Zhijiang, Hubei, China
Wuhan Better Organic Technology Inc.

Contact:13307163183

Address:Wuhan Economic&Technology Development Zone, Hubei

Relevant to this article

Tyrosine kinase inhibitors. 14. Structure-activity relationships for methyl-amino-substituted derivatives of 4-[3-bromophenyl)amino]-6- (methylamino)-pyrido[3,4-d]pyrimidine (PD 158780), a potent and specific inhibitor of the tyrosine kinase activity of receptors for the EGF family of growth factors

Doi:10.1021/jm970641d
(1998)
Doi:10.1021/ja01310a036
(1935)
A new efficient method for the three-component synthesis of 4(3H)-Quinazolinones

Doi:10.3987/COM-08-11437
(2008)
Doi:10.1002/jps.2600571039
(1968)
Pd-catalyzed carbonylative cycloamidation of ketoimines for the synthesis of pyrido[1,2-a]pyrimidin-4-ones

Doi:10.1039/c5cc02631h
(2015)
Palladium-Catalyzed Additions of Alkenyl Epoxides to Pronucleophiles: A Synthesis of the Macrolactam Aglycone of Fluviricin B1

Doi:10.1002/anie.199714861
(1997)

Article Doi