A concise synthetic entry to substituted 2-Aminothieno[2,3- d]pyrimidines via a Gewald precursor

DOI: 10.1016/S0960-894X(97)00283-7

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Bioorganic and Medicinal Chemistry Letters p. 1629 - 1634 (1997)

Update date:2022-08-03

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Authors:

Zhang, Minsheng

Harper, Richard W.

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Article abstract of DOI:10.1016/S0960-894X(97)00283-7

A concise synthesis of substituted 2-aminothieno[2,3-d]pyrimidines is described based on pyrimidine annulation of tetrasubstituted thiophene precursors assembled by a Gewald thiophene ring synthesis.

Full text of DOI:10.1016/S0960-894X(97)00283-7

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