An efficient synthesis of short-chain sphingomyelin analogs and their susceptibility to hydrolysis catalyzed by sphingomyelinase

DOI: 10.1016/S0960-894X(97)00298-9

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 1725 - 1728 (1997)

Update date:2022-08-04

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Authors:

Murakami, Masahiro

Iwama, Seiji

Fujii, Shinobu

Ikeda, Kiyoshi

Katsumura, Shigeo

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Article abstract of DOI:10.1016/S0960-894X(97)00298-9

An efficient synthesis of (D)-erythro-sphingomyelin analogs was achieved v/a highly stereoselective reduction of 3-benzyl-4-(alkynyloxo)-oxazolidinone with diisobutylaluminum phenoxide reagent. The initial velocities of the hydrolysis of the (D)-erythro-d

Full text of DOI:10.1016/S0960-894X(97)00298-9

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