Synthesis of regiospecifically substituted 2-hydroxybenzocyclobutenones

DOI: 10.1139/v97-098

Source and publish data:

Canadian Journal of Chemistry p. 817 - 824 (1997)

Update date:2022-09-26

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Authors:

Lear, Yvonne

Durst, Tony

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Article abstract of DOI:10.1139/v97-098

Regiospecifically substituted 2-hydroxybenzocyclobutenones were synthesized from the corresponding TBS protected 2-bromo-mandelate esters via halogen-metal exchange, cyclization, and subsequent deprotection.

Full text of DOI:10.1139/v97-098

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Product name:(2-Bromo-6-methoxy-phenyl)-trimethylsilanyloxy-acetonitrile

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