Synthesis and biological evaluation of 1α,24-dihydroxy-25-nitrovitamin D3

DOI: 10.1016/S0960-894X(99)00013-X

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 381 - 384 (1999)

Update date:2022-08-04

Topics:

Authors:

Oshida, Jun-Ichi

Okamoto, Makoto

Ishizuka, Seiichi

Azuma, Shizuo

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Article abstract of DOI:10.1016/S0960-894X(99)00013-X

1α,24(R)-Dihydroxy-25-nitrovitamin D₃ 1 and 1α,24(S)-dihydroxy-25- nitrovitamin D₃ 2 were synthesized using the palladium-catalyzed alkylative enyne cyclization reaction. Their biological properties were studied based on VDR binding

Full text of DOI:10.1016/S0960-894X(99)00013-X

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Product name:Benzoic acid (1R,3aR,4S,7aR)-1-((1R,4R)-4-hydroxy-1,5-dimethyl-5-nitro-hexyl)-7a-methyl-octahydro-inden-4-yl ester

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