Trisubstituted benzene leukotriene B4 receptor antagonists: Synthesis and structure-activity relationships

DOI: 10.1016/S0968-0896(97)00089-8

Source and publish data:

Bioorganic and Medicinal Chemistry p. 1649 - 1674 (1997)

Update date:2022-08-03

Topics:

Authors:

Konno, Mitoshi

Nakae, Takahiko

Sakuyama, Shigeru

Odagaki, Yoshihiko

Nakai, Hisao

Hamanaka, Nobuyuki

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0968-0896(97)00089-8

A series of trisubstituted benzenes which demonstrate leukotriene B₄ (LTB₄, 1) receptor affinity was prepared. Previous trisubstituted benzenes from our laboratory showed high affinity to the LTB₄ receptor but demonstrated

Full text of DOI:10.1016/S0968-0896(97)00089-8

Products guided by the article

Product name:ethyl-5-{4-[2-(ethoxycarbonyl)-(E)-ethenyl]3-hydroxyphenoxy}pentanoate

Cas No:197708-28-4

R&D Labs maybe for 197708-28-4

HANGZHOU ZHONGCHANG SCIENTIFIC CO.,LTD

Contact:+86-571-88932183

Address:Hangzhou
shijiazhuang shuanglian chemical industry co.,ltd

Contact:0311-82190302

Address:Luquan Intersection , Shijiazhuang--Taiyuan Expressway，Shijiazhuang City
Wuhan Pengo Technology.,Ltd.

Contact:+86-27-67841589

Address:Add: 999 Gaoxin Road, Donghu New Technology Development Zone, Wuhan City, Hubei, China
Guangzhou Puho Pharmaceutical Technology Co. Ltd.

Contact:86-20-29848035/29848075

Address:No.166, Chaoyang East Road, Panyu District, Guangzhou City, Guangdong Province
YanCheng LongShen Chemical Co.,Ltd.

Contact:+86-515-86668866

Address:No.13,Weiyi Road,Funing Aoyang Industrial Park

Relevant to this article

Synthesis of a new C₂-symmetric molecule with dimeric hydroxyethylene isosteric moiety

Doi:10.1080/00397919708005464
(1997)
Siamyl Glyoxylate as an Efficient Enophile in the Lewis Acid Mediated Glyoxylate Ene-Reaction with Allylic Ethers. Application to the Synthesis of a Taxol A-Ring Subunit

Doi:10.1021/jo971082l
(1997)
Asymmetric Cyclopropanation of Allylic Ethers: Cleavage and Regeneration of the Chiral Auxiliary

Doi:10.1021/jo00056a028
(1993)
Intramolecular [2+3]-addition of an azide to a C=C double bond as a novel approach to piperazines

Doi:10.1016/j.tetlet.2004.12.071
(2005)
Synthesis and biological properties of new constrained CCK-B antagonists: Discrimination of two affinity states of the CCK-B receptor on transfected CHO cells

Doi:10.1021/jm970439a
(1997)
Insertion of ethyne into the Ru-B bond of a coordinatively unsaturated ruthenium boryl complex. X-ray crystal structure of Ru(CH=CH[BOC₆H₄O])Cl(CO)(PPh₃)₂

Doi:10.1021/om970618q
(1997)

Article Doi