Trisubstituted benzene leukotriene B4 receptor antagonists: Synthesis and structure-activity relationships

DOI: 10.1016/S0968-0896(97)00089-8

Source and publish data:

Bioorganic and Medicinal Chemistry p. 1649 - 1674 (1997)

Update date:2022-08-03

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Authors:

Konno, Mitoshi

Nakae, Takahiko

Sakuyama, Shigeru

Odagaki, Yoshihiko

Nakai, Hisao

Hamanaka, Nobuyuki

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Article abstract of DOI:10.1016/S0968-0896(97)00089-8

A series of trisubstituted benzenes which demonstrate leukotriene B₄ (LTB₄, 1) receptor affinity was prepared. Previous trisubstituted benzenes from our laboratory showed high affinity to the LTB₄ receptor but demonstrated

Full text of DOI:10.1016/S0968-0896(97)00089-8

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