Tetrahedron Letters p. 7851 - 7852 (1997)
Update date:2022-08-04
Topics:
Whitehouse, Darren L.
Savinov, Sergey N.
Austin, David J.
Photolabile linkers have become an important orthogonal technique for substrate cleavage off the resin in solid-phase organic synthesis. Herein, we report an improved synthesis and selective coupling of a hydroxy based photolinker to a hydroxy based solid-phase resin, thereby removing the necessity for protection or on-resin manipulation.
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Doi:10.1016/0040-4039(81)80003-2
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