Synthesis and Structure Elucidation of a New Potent Sandalwood-Oil Substitute

Article abstract of DOI:10.1002/hlca.19980810545

New derivatives of campholenaldehyde ( = 2-(2,2,3-trimethylcyclopent-3-enyl)ethanal) bearing two cyclopropane moieties were synthesized, and the structure of the stereoisomer responsible for its exceptionally strong, diffusive, and natural sandalwood-oil scent, ((1S,2S)-1-methyl-2-{[(1S,3R,5R)-1,2,2-trimethylbicyclo[3.1.0]hex-3- yl]methyl}cyclopropyl)methanol (13a), was elucidated.